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As the official influenza season begins, it’s important to find ways to keep winter’s ever-present illness at bay. That’s especially true this year, as one in every 20 outpatient doctor visits will be for the flu, as influenza is commonly known—twice what it is in an average year.

But dealing with the virus that causes the flu can be tricky. Health officials recommend getting a yearly flu vaccine, and they urge everyone to protect themselves with one time-honored tactic: wash your hands, well and often. That may be the single best way to stop the disease in its tracks.

But in case you find yourself facing an encroaching onslaught of the illness though coworkers or school-age kids, This Old House has a few strategies to make life as hard as possible for the flu—or any germs, for that matter—to take root in your house.

Tip 1: Watch Out for Germy Hot Spots

The sink, the telephone, children’s toys, and doorknobs are popular landing sites for virus and bacteria. If someone is sick at home, disinfect daily, especially the remote control and the phone. Charles Gerba, microbiologist and author of The Germ Freak’s Guide to Outwitting Colds and Flu, says remote controls and countertops can be the germiest locale in the whole house. “What’s the first thing you do after you call in sick? Pick up the remote control,” he says. “Sixty percent of them contain influenza virus in the home of a sick person.”

In fact, Gerba says, remote controls are the germiest thing in hotel and hospital rooms. And since a virus like influenza spreads through touching something a sick person has also touched, or an object that’s been sneezed on, cleaning off the places your hand usually goes is most important.

Find out more from Health.com about the germiest places you’re likely to encounter during an average day.

Tip 2: Disinfect the Desk

According to Gerba, the home office is another place to watch out for germs. “Desktops have 400 times more bacteria than a toilet seat,” he says.

Gerba says to disinfect your desktop weekly, along with the rest of the house. This could reduce your exposure to colds and flu by as much as 50 percent.

Tip 3: Don’t Forget the Sponge

Your kitchen sponge should be replaced every couple of weeks. If that runs counter to your frugal ways, you can microwave it for one minute or run it in the dishwasher to eliminate germs.